These bullets are slightly larger and somewhat more powerful than a .22. There are numerous firearms that use this caliber, but this ammo is a bit more expensive without any real added benefit apart from reliability of center-fire casings.
Pros: The stopping power is slightly more than .22 but there isn’t much of a difference. Both get the job done, but this one leaves a slightly larger hole.
Cons: The con of this round is the same as .22, really. It’s a small round and most .25 caliber guns aren’t that popular.